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Komzifti

Komzifti is an advanced anticancer therapy developed for the treatment of adults with relapsed or refractory Acute Myeloid Leukemia (AML) harboring a susceptible Nucleophosmin 1 (NPM1) mutation. It is specifically indicated for patients who have no satisfactory alternative treatment options, addressing a critical unmet medical need in high-risk AML management.

Designed to target the molecular pathways driven by NPM1 mutations, Komzifti provides a focused therapeutic approach aimed at improving disease control in a population with limited clinical responses to conventional regimens. Its formulation and mechanism are optimized to support enhanced antileukemic activity while maintaining rigorously monitored safety and quality standards.

Komzifti serves as a promising option for clinicians seeking mutation-specific therapy in relapsed or refractory AML, offering renewed possibility in cases where traditional treatments have proven insufficient.

Molecule Details :

  • Molecule Name :

    Ziftomenib
  • Innovator :

    KURA ONCOLOGY INC
  • Approval Date :

    13-Nov-25
  • NCE-1 Date :

    13-Nov-29
  • NCE Date :

    13-Nov-30
  • Dosage Form :

    Oral Capsule
  • Strength :

    200MG
  • Therapeutic Category :

    Anticancer
  • Revenue ($M) :

    NA

Year-wise Projected Sales ($M) :

  • 2025 :

    NA
  • 2026 :

    69
  • 2027 :

    202
  • 2028 :

    397
  • 2029 :

    623
  • 2030 :

    978
  • 2031 :

    1,370
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