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Loargys

Pegzilarginase-Nbln
Metabolic Enzyme Replacement Therapy
Injection

Loargys (pegzilarginase-nbln) is indicated for the treatment of Arginase 1 Deficiency (ARG1-D), also known as hyperargininemia, in adult and pediatric patients 2 years of age and older, a rare urea cycle disorder characterized by elevated plasma arginine levels and progressive neurological impairment.

Loargys functions as an enzyme replacement therapy, reducing toxic arginine accumulation and helping to manage the metabolic and neurological complications associated with the disease.

Approval Date
23-Feb-26
Data Exclusivity Expiry
23-Feb-30
Market Exclusivity Expiry
23-Feb-38
Commercial snapshot

Market performance & projections

Revenue ($M)
NA
CAGR (%)
NA
Projected sales, 2026–2032 ($M)
Analyst projection, $M per year
2026
NA
2027
NA
2028
NA
2029
NA
2030
NA
2031
NA
2032
NA
Molecule profile

Details & specifications

Molecule
Pegzilarginase-Nbln
Innovator
IMMEDICA PHARMA AB
Dosage Form
Injection
Strength
0.1 mg/kg
Therapeutic Category
Metabolic Enzyme Replacement Therapy
Usage
To treat hyperarginemia in adults and pediatric patients two years and older with arginase 1 deficiency, in conjunction with dietary protein restriction
Good to know

Frequently asked questions

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