Lynavoy (linerixibat) is a prescription medication used in adults to treat cholestatic pruritus associated with primary biliary cholangitis (PBC), a chronic liver disease marked by bile acid buildup and persistent itching.

Unlike conventional symptomatic treatments, Lynavoy works by inhibiting the ileal bile acid transporter (IBAT) in the intestine, reducing bile acid reabsorption and promoting their elimination. This helps lower circulating bile acid levels and directly targets the cause of itching.

Cholestatic pruritus can significantly impact sleep, daily functioning, and overall quality of life. With targeted therapies like Lynavoy, patients can experience meaningful relief and improved comfort.

Lynavoy is taken orally and is intended for ongoing management under medical supervision.