Verquvo-Vericiguat
Heart failure care has long relied on drugs that ease the heart’s workload, but patients who have just been hospitalized for a worsening episode remain at very high risk. Verquvo (vericiguat) was approved to address that specific window. By stimulating soluble guanylate cyclase, Verquvo restores nitric oxide signaling to relax blood vessels and improve cardiac […]
Mimrylo-Rusfertide Acetate
For patients with polycythemia vera, managing excess red blood cell production can often involve frequent phlebotomy. Mimrylo (rusfertide) takes a different approach by working with the body’s natural iron-regulation system. By mimicking hepcidin, a hormone that controls iron availability, Mimrylo helps limit the iron needed to produce new red blood cells. This offers a new […]
Lisraya-Brepocitinib
Dermatomyositis can affect both physical strength and quality of life, yet treatment options specifically developed for the condition have remained limited. Lisraya (brepocitinib) introduces a new oral treatment option for adults living with this rare autoimmune disease. Its approval represents an important step in the development of targeted therapies for dermatomyositis and adds a new […]
Rasonque-Daraxonrasib
Pancreatic cancer remains one of the most challenging cancers to treat, partly because of the limited number of effective targeted therapies available. Rasonque (daraxonrasib) brings attention to one of the most important pathways driving tumour growth: RAS. Taken as a once-daily oral therapy, Rasonque targets multiple forms of the RAS protein and is approved for […]
Zenbexus-Iberdomide Hydrochloride
Treatment for multiple myeloma continues to evolve as patients move through different lines of therapy. Zenbexus (iberdomide) adds a new option to the treatment landscape for patients who have already received prior therapies. Used in combination with daratumumab and hyaluronidase-fihj and dexamethasone, Zenbexus is intended for adults with multiple myeloma who have previously received a […]
Tauklarify-Florquinitau F 18
Alzheimer’s disease research is increasingly focused on understanding what is happening inside the brain, not just observing symptoms. Tauklarify (florquinitau F 18) supports this effort by enabling the visualization of tau pathology through PET imaging. Used in adults with cognitive impairment being evaluated for Alzheimer’s disease, Tauklarify helps identify tau neurofibrillary tangles, one of the […]
Orzeyful-Oveporexton
Narcolepsy type 1 affects far more than daytime sleepiness. For many patients, managing the condition means dealing with a range of symptoms linked to the loss of orexin signaling. Orzeyful (oveporexton) brings a new approach by directly targeting this underlying pathway. As an oral orexin receptor 2 agonist, Orzeyful is designed to restore the signaling […]
Simtriyo-Centanafadine
Not every patient with ADHD is a candidate for stimulant therapy. Simtriyo introduces a different approach as an FDA-approved non-stimulant treatment that works by inhibiting the reuptake of norepinephrine, dopamine, and serotonin. Instead of relying on traditional stimulant mechanisms, Simtriyo modulates three key neurotransmitter systems involved in attention, focus, and impulse control. This triple reuptake […]
Jideytro-Zidesamtinib
Patients with ROS1-positive non-small cell lung cancer often have limited options once resistance develops to earlier targeted therapies. Jideytro (zidesamtinib) addresses this need as a next-generation ROS1-selective kinase inhibitor approved for adults whose disease has progressed after prior ROS1 inhibitor treatment. Designed with high selectivity and strong penetration into the central nervous system, Jideytro aims […]
Lipfendra-Enlicitide Decanoate
PCSK9 inhibitors have transformed cholesterol management, but until now they have largely depended on injections. Lipfendra (enlicitide decanoate) changes that by becoming the first FDA-approved oral PCSK9 inhibitor for lowering LDL cholesterol. The therapy works by blocking PCSK9, allowing more LDL receptors to remain active on the liver and clear harmful cholesterol from the bloodstream. […]
